Why Insight Genome?
Every individual has three billion “letters” in their DNA. Those letters make up their genome. What makes every human unique is the four to six million letters that are different. Unless you are an identical twin, no one else shares your genetic makeup. Those four to six million differences are called variants. Some of those variants are responsible for innocuous differences such as hair or eye color, the shape of your nose, or your adult height. Other variants are linked to disease.
Of those variants linked to disease, some are well-established as pathogenic—we know there is a high likelihood of causing disease. A specific change to the breast cancer gene BRCA1 is an example of a pathogenic variant.
Other variants indicate you are a carrier of a disease. While you may not have the disease (example: cystic fibrosis), you may have a chance of passing it along to your children.
These are the types of variants that are included in the Clinical Report. The Clinical Report will be returned to the Smith Family Clinic. A physician and genetic counselor at the clinic will share those results with you. That report will include information about genetic changes, or variants, that are known to be linked to specific medical conditions; the diseases you “carry” and have a chance at passing along to your children, and specific cancers for which there are inherited genetic links.